Description

Trityldimethylbromosilane is a specialized organosilicon reagent featuring a sterically hindered trityl group and a reactive bromosilane moiety. This compound is a critical building block in advanced organic synthesis, particularly for the protection of sensitive functional groups and the construction of complex molecular architectures. It is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable intermediates for demanding synthetic routes.

Application

• Protecting Group Reagent: Used as a robust protecting agent for alcohols, diols, and other nucleophiles in multi-step organic synthesis.
• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Employed in the development of novel pesticides and herbicides where selective protection is required.
• Material Science: Utilized in the surface functionalization of silicon-based materials and the synthesis of specialized silicone polymers.
• Cross-Coupling Reactions: Acts as an electrophilic silicon source in transition metal-catalyzed cross-coupling reactions.
• Nucleoside & Carbohydrate Chemistry: Applied in the selective protection of sugar hydroxyl groups during the synthesis of nucleosides and complex carbohydrates.

Basic Information

Product Name	Trityldimethylbromosilane
CAS No.	62092-85-7
Molecular Formula	C21H21BrSi
Molecular Weight	381.38 g/mol
Synonyms	Bromo(trityl)dimethylsilane; Dimethyl(trityl)bromosilane; Triphenylmethyl(dimethyl)bromosilane; Bromodimethyl(trityl)silane; Trityldimethylsilyl bromide; (Triphenylmethyl)dimethylbromosilane; TDMBS; Contact for additional names.
EINECS	Contact for details

Quality Control

Our Trityldimethylbromosilane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We provide comprehensive analytical data including HPLC and NMR verification. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.