Description

(8-Beta)-9,10-Didehydro-6-Methyl-Ergoline-8-Carbonyl Azide is a specialized ergoline derivative, a key synthetic intermediate in the production of complex pharmaceutical compounds. Its value lies in its reactive azide functional group, which enables crucial transformations like the Staudinger reduction or Huisgen cycloaddition for building advanced molecular architectures. This high-purity intermediate is essential for research and development chemists and process development teams in the pharmaceutical and fine chemical industries, particularly those focused on developing novel therapeutics within the ergot alkaloid class.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel ergot alkaloid derivatives and other complex bioactive molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Process Chemistry: Serves as a key precursor in the scalable synthesis of target active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential use in the development of labeled compounds or probes for studying biological pathways.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes requiring a reactive azide handle for click chemistry or amide bond formation.

Basic Information

Product Name	(8-Beta)-9,10-Didehydro-6-Methyl-Ergoline-8-Carbonyl Azide
CAS No.	62074-28-6
Molecular Formula	C₁₉H₂₁N₅O
Molecular Weight	335.41 g/mol
Synonyms	6-Methyl-9,10-didehydroergoline-8β-carbonyl azide; 8β-Carbazoyl-6-methyl-9,10-didehydroergoline; Lysergol-8-carbonyl azide derivative; 6-Methyl-δ9,10-ergolene-8β-carboxylic acid azide; Ergoline-8-carbonyl azide, 6-methyl-9,10-didehydro-; (8β)-9,10-Didehydro-6-methylergoline-8-carboxylic acid azide
EINECS	Contact for details

Quality Control

Our (8-Beta)-9,10-Didehydro-6-Methyl-Ergoline-8-Carbonyl Azide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its light-sensitive nature and reactive azide group, prolonged exposure to light, heat, or moisture should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.