Description

3-(2-Chlorophenyl)-5-Nitro-1H-Indole-2-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-based heterocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, especially within oncology and CNS research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel indole-based drug candidates.
• Oncology Research: Used in the development of targeted cancer therapies and kinase inhibitors.
• CNS Drug Discovery: Serves as a precursor for compounds targeting neurological disorders.
• Agrochemical Synthesis: Intermediate for creating advanced crop protection agents with specific activity.
• Material Science Research: Investigated for the development of organic electronic materials and dyes.
• Biochemical Tool Compound: Used in assay development and proteomics research to study biological pathways.

Basic Information

Product Name	3-(2-Chlorophenyl)-5-Nitro-1H-Indole-2-Carbonitrile
CAS No.	62039-78-5
Molecular Formula	C15H8ClN3O2
Molecular Weight	297.70 g/mol
Synonyms	5-Nitro-3-(2-chlorophenyl)-1H-indole-2-carbonitrile; 2-Chloro-5-nitro-3-phenyl-1H-indole-2-carbonitrile; 3-(2-Chlorophenyl)-5-nitroindole-2-carbonitrile; 62039-78-5; 1H-Indole-2-carbonitrile, 3-(2-chlorophenyl)-5-nitro-; 5-Nitro-3-(o-chlorophenyl)indole-2-carbonitrile; 3-(2-Chlorophenyl)-5-nitro-1H-indole-2-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 3-(2-Chlorophenyl)-5-Nitro-1H-Indole-2-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is released with a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for pharmaceutical intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.