Description

1-Acetyl-5-Bromoindole is a high-purity brominated indole derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable building blocks for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Material Science Precursor: Serves as a monomer or precursor for functional polymers and organic electronic materials.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies in heterocyclic and cross-coupling chemistry.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying biological pathways and protein functions.
• Custom Synthesis: A starting point for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	1-Acetyl-5-Bromoindole
CAS No.	61995-52-6
Molecular Formula	C10H8BrNO
Molecular Weight	238.08 g/mol
Synonyms	5-Bromo-1-acetylindole; 5-Bromo-1H-indol-1-yl ethanone; 1-(5-Bromo-1H-indol-1-yl)ethanone; 5-Bromoindole-1-acetic acid methyl ester (common misnomer); N-Acetyl-5-bromoindole; 5-Bromo-N-acetylindole; 1-Acetyl-5-bromo-1H-indole; Ethanone, 1-(5-bromo-1H-indol-1-yl)-
EINECS	Contact for details

Quality Control

Our 1-Acetyl-5-Bromoindole is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.