Description

N,n-Dimethylformamide, [Carbonyl-14C] CAS NO 61853-17-6 is a carbon-14 radiolabeled analog of the versatile polar aprotic solvent N,N-Dimethylformamide (DMF). This compound is essential for advanced research and development, enabling precise metabolic and pharmacokinetic studies through radioisotope tracing. It is a critical tool for scientists and quality control professionals in the pharmaceutical, agrochemical, and life science industries who require high-specific-activity materials for autoradiography, ADME (Absorption, Distribution, Metabolism, and Excretion) studies, and environmental fate analysis.

Application

• Pharmaceutical R&D: As a radiolabeled solvent and reagent in the synthesis of carbon-14 labeled drug candidates for metabolism and pharmacokinetic (PK/PD) studies.
• Metabolic Pathway Tracing: Used in autoradiography and liquid scintillation counting (LSC) to track the distribution and biotransformation of compounds in biological systems.
• Agrochemical Research: Employed in the development and environmental fate studies of labeled pesticides and herbicides.
• Chemical Synthesis: Acts as a radiolabeled precursor or solvent in organic synthesis for introducing the carbonyl-14C moiety into target molecules.
• Quality Control & Reference Standards: Serves as an internal standard or tracer in analytical method development and validation within GLP/GMP environments.

Basic Information

Product Name	N,n-Dimethylformamide, [Carbonyl-14C]
CAS No.	61853-17-6
Molecular Formula	C14COH7N or C3H714CON
Molecular Weight	~74.08 g/mol (varies with specific activity)
Synonyms	DMF-[carbonyl-14C]; [14C]-DMF; N,N-Dimethyl[14C]formamide; [Carbonyl-14C]-N,N-Dimethylformamide; Formdimethylamide-14C; NSC 5356 (labeled); Radiolabeled DMF; 14C-Labeled Dimethylformamide
EINECS	Contact for details

Quality Control

Every batch of N,n-Dimethylformamide, [Carbonyl-14C] is manufactured and analyzed under strict quality systems to ensure identity, purity, and specific activity. Our products undergo rigorous quality testing, including radiochemical purity analysis by HPLC with radiometric detection, to ensure compliance with research and GLP standards. A comprehensive Certificate of Analysis (COA) detailing specific activity, radiochemical purity, chemical purity, and solvent composition is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at recommended temperatures (typically 2-8°C or as specified on the label). This product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere if specified to maintain stability and specific activity. Follow all applicable radiation safety regulations for storage and handling.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Specific Activity	Customizable (mCi/mmol)
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (GC/HPLC)	≥ 99%
Solvent (if applicable)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.