Description

Levorphanol Hydrochloride is a potent synthetic opioid analgesic of the morphinan chemical class. This high-purity active pharmaceutical ingredient (API) is critical for the development and manufacturing of specialized pain management medications. It is primarily utilized by pharmaceutical companies and research institutions engaged in advanced analgesic formulation, clinical research, and neuropharmacological studies.

Application

• Pharmaceutical API: Core active ingredient in the formulation of potent prescription analgesics for severe, chronic, and breakthrough pain.
• Clinical Research: Used in controlled studies investigating pain pathways, opioid receptor pharmacology, and comparative analgesic efficacy.
• Reference Standard: Serves as a high-purity analytical standard for quality control laboratories in pharmaceutical manufacturing and regulatory testing.
• Neuropharmacology R&D: A key compound in preclinical research exploring central nervous system (CNS) targets and novel mechanisms for pain modulation.
• Hospital Compounding: Employed in specialized pharmacy compounding for tailored pain management solutions under strict medical supervision.

Basic Information

Item	Detail
Product Name	Levorphanol Hydrochloride
CAS No.	61734-47-2
Molecular Formula	C17H23NO • HCl
Molecular Weight	293.83 g/mol (Free base: 257.37 g/mol)
Synonyms	Levorphanol HCl; (-)-3-Hydroxy-N-methylmorphinan Hydrochloride; Levo-Dromoran; Levorphan Hydrochloride; NSC-25141; Ro 1-5470/7; (-)-Levorphanol Hydrochloride; 17-Methylmorphinan-3-ol Hydrochloride
EINECS	Contact for details

Quality Control

Our Levorphanol Hydrochloride is manufactured and tested under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) documenting compliance with relevant in-house or client-specific specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.