Description

2-Thiophenecarboxylic Acid, [Carboxyl-14C] is a carbon-14 labeled derivative of 2-thiophenecarboxylic acid, a key heterocyclic building block. This radiolabeled compound is essential for conducting precise metabolic, pharmacokinetic, and environmental fate studies, providing critical data for regulatory submissions and scientific research. It is primarily utilized by pharmaceutical R&D teams, agrochemical scientists, and contract research organizations (CROs) engaged in advanced tracer and analytical chemistry.

Application

• Tracer Studies in Drug Metabolism and Pharmacokinetics (DMPK): Used to track the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities in preclinical and clinical research.
• Agrochemical Environmental Fate Analysis: Employed to study the degradation pathways, soil metabolism, and residue analysis of pesticides and herbicides.
• Biochemical Pathway Elucidation: Aids in mapping specific metabolic pathways and identifying novel metabolites in biological systems.
• Reference Standard for Analytical Method Development: Serves as a critical standard for validating sensitive analytical methods like LC-MS and HPLC in bioanalysis.
• Material Science Research: Can be used as a tagged monomer or intermediate in the synthesis of radiolabeled polymers or conductive materials for tracking purposes.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, [Carboxyl-14C]
CAS No.	61714-13-4
Molecular Formula	C5H414CO2S
Molecular Weight	~130.16 g/mol (calculated with 14C)
Synonyms	2-Thenoc Acid-14C; 2-Thiophene-14C-carboxylic Acid; α-14C-2-Thiophenecarboxylic Acid; 2-Carboxy-14C-thiophene; Thiophene-2-carboxylic-14C Acid; [Carbonyl-14C]-2-thiophenecarboxylic acid; T2CA-14C; 2-Thenoic-14C Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Thiophenecarboxylic Acid, [Carboxyl-14C] is manufactured and analyzed under strict quality systems to ensure traceability, purity, and specific activity consistency. We provide comprehensive Certificates of Analysis (COA) detailing radiochemical purity, chemical purity, specific activity, and solvent content, supported by validated analytical methods (HPLC, NMR, MS). Our quality commitment aligns with the standards expected for radiolabeled compounds in GLP-compliant research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) to maintain stability. Handle and store in accordance with all local, national, and international regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR/NMR)	Conforms to structure
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for specific batch data)
Solvent (Residual)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.