Description

1H-Indole,5-Ethynyl-1-Methyl-(9Ci) CAS NO 61640-21-9 is a specialized indole derivative featuring an ethynyl substituent, serving as a versatile and high-value synthetic building block. This compound is critical for advanced research and development in medicinal chemistry, enabling the synthesis of novel molecular architectures. It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and academic institutions focused on heterocyclic chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted small molecule drugs, particularly those exploring indole-based scaffolds for oncology and CNS disorders.
• Agrochemical Research: Used in developing new active ingredients for crop protection, leveraging its heterocyclic core for bioactivity.
• Material Science: Building block for advanced organic materials, including polymers and ligands for catalytic systems, due to its ethynyl functional group.
• Academic & R&D: Essential reagent for methodological studies in organic synthesis, including cross-coupling reactions and click chemistry applications.
• Chemical Biology: Employed in the design and synthesis of molecular probes and inhibitors for studying biological pathways.

Basic Information

Product Name	1H-Indole,5-Ethynyl-1-Methyl-(9Ci)
CAS No.	61640-21-9
Molecular Formula	C11H9N
Molecular Weight	155.20 g/mol
Synonyms	5-Ethynyl-1-methyl-1H-indole; 1-Methyl-5-ethynylindole; 5-Ethynyl-1-methylindole; 1H-Indole, 5-ethynyl-1-methyl-; 5-Ethynyl-1-methyl-1H-indole (9CI); 5-Ethynyl-1-methylindole; 1-Methyl-5-ethynyl-1H-indole
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemicals. Each batch of 1H-Indole,5-Ethynyl-1-Methyl-(9Ci) is analyzed to ensure high purity and consistency, supported by a comprehensive Certificate of Analysis (COA). Our quality system is designed to meet the exacting standards of research and development, with specifications typically aligned with >95% purity (HPLC).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.