Description

2-(1,1,2,2-Tetrafluoroethyl)-1H-Benzimidazole is a specialized fluorinated heterocyclic compound that serves as a high-value building block in advanced chemical synthesis. Its unique structure, featuring a benzimidazole core with a tetrafluoroethyl side chain, makes it a critical intermediate for developing novel materials and active pharmaceutical ingredients. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and antiviral applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atoms contribute to improved bioavailability and environmental stability.
• Ligand for Catalysis: Serves as a sophisticated ligand in transition metal catalysis for facilitating challenging cross-coupling and fluorination reactions.
• Advanced Material Research: Employed in the creation of organic semiconductors, liquid crystals, and polymers requiring specific electronic and thermal properties.
• Fluorine Chemistry Building Block: Essential for introducing the tetrafluoroethyl moiety into complex molecules in medicinal and materials chemistry.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	2-(1,1,2,2-Tetrafluoroethyl)-1H-Benzimidazole
CAS No.	61532-00-1
Molecular Formula	C9H5F4N2
Molecular Weight	217.14 g/mol
Synonyms	2-(1,1,2,2-Tetrafluoroethyl)-1H-benzimidazole; 2-(Perfluoroethyl)benzimidazole; 1H-Benzimidazole, 2-(1,1,2,2-tetrafluoroethyl)-; 2-(Tetrafluoroethyl)benzimidazole; 2-(1,1,2,2-Tetrafluoroethyl)benzimidazole; Benzimidazole, 2-(1,1,2,2-tetrafluoroethyl)-; 61532-00-1; 2-(Tetrafluoroethyl)-1H-benzimidazole
EINECS	Contact for details

Quality Control

Every batch of 2-(1,1,2,2-Tetrafluoroethyl)-1H-Benzimidazole is produced and tested under strict quality management systems to ensure consistency and reliability for your critical R&D and scale-up processes. We provide comprehensive analytical data including HPLC purity, NMR confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is supplied with each shipment, and we support custom purity specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.