Description

4-Bromoaniline-2,3,5,6-D4 is a deuterium-labeled analog of 4-bromoaniline, a key intermediate in organic synthesis and analytical chemistry. This isotopically labeled compound is essential for applications requiring precise tracking and quantification, such as in mass spectrometry and metabolic studies. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing deuterated active pharmaceutical ingredients (APIs), creating internal standards, and conducting mechanistic studies.

Application

• Deuterated Pharmaceutical Intermediate: Serves as a critical building block for synthesizing deuterium-labeled drug candidates, which can offer improved metabolic stability and pharmacokinetic profiles.
• Internal Standard for Analytical Chemistry: Used as a high-purity internal standard in quantitative analysis via LC-MS, GC-MS, and NMR spectroscopy to ensure accurate measurement of 4-bromoaniline in complex matrices.
• Metabolic Pathway Tracing: Employed in drug metabolism and pharmacokinetics (DMPK) studies to trace and elucidate metabolic pathways and degradation products.
• Agrochemical Research: Utilized in the development and analysis of novel deuterated agrochemicals and their environmental fate.
• Organic Synthesis & Catalysis Research: Acts as a specialized reagent in cross-coupling reactions and other synthetic transformations where isotopic labeling is required for mechanistic investigation.
• Material Science: A precursor for synthesizing deuterated dyes, pigments, and advanced polymers for specialized optical and electronic applications.

Basic Information

Product Name	4-Bromoaniline-2,3,5,6-D4
CAS No.	61357-76-4
Molecular Formula	C6D4BrN
Molecular Weight	176.03 g/mol
Synonyms	4-Bromo-2,3,5,6-tetradeuteroaniline; p-Bromoaniline-d4; 1-Amino-4-bromobenzene-2,3,5,6-d4; 4-Bromobenzenamine-d4; Deuteronated 4-Bromoaniline; [2,3,5,6-2H4]-4-Bromoaniline; Perdeuterated 4-Bromoaniline (on the ring); 4-Bromo-aniline-d4
EINECS	Contact for details

Quality Control

Our 4-Bromoaniline-2,3,5,6-D4 is manufactured under strict quality systems to ensure high isotopic and chemical purity for research and development. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry to confirm deuterium incorporation and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment (NMR/MS)	≥98 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.