Description

1-Bromo-4-Acetanilide-D4 is a deuterated derivative of 1-Bromo-4-Acetanilide, where four hydrogen atoms are replaced with deuterium. This isotopic labeling makes it an essential internal standard and tracer in quantitative analytical methods, particularly mass spectrometry, ensuring high accuracy and reliability in measurement. It is primarily used by researchers and quality control laboratories in the pharmaceutical, agrochemical, and advanced material science sectors for method development, metabolic studies, and impurity profiling.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical reference compound in LC-MS and GC-MS for the accurate quantification of its non-deuterated counterpart and related metabolites.
• Pharmaceutical Research & Development: Used in drug metabolism and pharmacokinetics (DMPK) studies as a stable isotope-labeled tracer to track compound absorption, distribution, metabolism, and excretion (ADME).
• Impurity Profiling and Method Validation: Essential for developing and validating analytical methods to identify and quantify impurities and degradants in active pharmaceutical ingredients (APIs).
• Agrochemical Analysis: Employed in the analysis of pesticides and herbicides to ensure regulatory compliance and environmental safety.
• Metabolite Identification: Aids in the structural elucidation of metabolites in biological matrices.
• Chemical Synthesis Research: Used as a building block in the synthesis of more complex deuterated compounds for research purposes.

Basic Information

Product Name	1-Bromo-4-Acetanilide-D4
CAS No.	61357-75-3
Molecular Formula	C8H4D4BrNO
Molecular Weight	216.07 g/mol (approx.)
Synonyms	N-(4-Bromophenyl)acetamide-d4; 4'-Bromoacetanilide-d4; p-Bromoacetanilide-d4; 4-Bromo-N-(phenyl-d4)acetamide; Acetamide, N-(4-bromophenyl)-, 2,3,5,6-tetradeuterio-; 1-Bromo-4-acetamidobenzene-d4; 4-Acetamidobromobenzene-d4
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Acetanilide-D4 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and MS, to confirm isotopic purity, chemical purity, and identity. We provide detailed Certificates of Analysis (COA) with each shipment, which include batch-specific data on assay, deuterium enrichment, and related substance profiles. Our commitment to traceability and consistency ensures the material meets the stringent requirements for analytical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.