Description

2,4-o-Benzylidene-D-Glucitol is a chemically protected derivative of D-glucitol (sorbitol), featuring a benzylidene acetal group at the 2,4-positions. This compound serves as a crucial chiral intermediate and protecting group reagent in sophisticated organic synthesis, enabling selective reactions in complex molecule construction. It is primarily utilized by pharmaceutical R&D and fine chemical industries for the production of specialized carbohydrates, nucleosides, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral building block for synthesizing nucleoside analogs and carbohydrate-based drugs.
• Carbohydrate Chemistry: Used in the selective protection and functionalization of sugar molecules for research and production.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in stereoselective catalytic reactions.
• Fine Chemical Production: Intermediate in the manufacture of specialty surfactants, complex polyols, and advanced materials.
• Biochemical Research: Tool compound for studying enzyme mechanisms and glycosylation processes.
• Polymer Science: Potential monomer or modifier for creating polymers with specific stereochemistry.

Basic Information

Product Name	2,4-o-Benzylidene-D-Glucitol
CAS No.	61340-09-8
Molecular Formula	C₁₃H₁₈O₆
Molecular Weight	270.28 g/mol
Synonyms	2,4-O-Benzylidene-D-sorbitol; 2,4-O-Benzylidene-D-glucitol; D-Glucitol, 2,4-O-benzylidene-; 2,4-O-(Phenylmethylene)-D-glucitol; Benzylidene-D-sorbitol; 1,3-O-Benzylidene-D-glucitol (common misassignment); D-Sorbitol, 2,4-O-benzylidene acetal; NSC 401016
EINECS	Contact for details

Quality Control

Our 2,4-o-Benzylidene-D-Glucitol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.