Description

Methyl 4-(2-Aminoanilino)-2,5-Dihydrothiophene-3-Carboxylate is a specialized heterocyclic organic compound featuring a unique dihydrothiophene core substituted with an aminoanilino moiety and a methyl ester group. This molecular architecture makes it a valuable and versatile chemical intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in the areas of medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Reagent: Serves as a precursor for constructing complex heterocyclic systems and fused ring structures in academic and industrial research laboratories.
• Material Science Precursor: Potential intermediate in the synthesis of organic semiconductors, dyes, or functional polymers due to its electron-rich thiophene derivative structure.
• Chemical Biology Probe Development: Utilized in creating tool compounds for studying biological pathways and target validation.

Basic Information

Product Name	Methyl 4-(2-Aminoanilino)-2,5-Dihydrothiophene-3-Carboxylate
CAS No.	61325-23-3
Molecular Formula	C12H14N2O2S
Molecular Weight	250.32 g/mol
Synonyms	Methyl 4-[(2-aminophenyl)amino]-2,5-dihydro-3-thiophenecarboxylate; 3-Thiophenecarboxylic acid, 2,5-dihydro-4-[(2-aminophenyl)amino]-, methyl ester; 4-(2-Aminoanilino)-2,5-dihydrothiophene-3-carboxylic acid methyl ester; Methyl 4-(2-aminoanilino)-2,5-dihydrothiophene-3-carboxylate; 2,5-Dihydro-4-[(2-aminophenyl)amino]-3-thiophenecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-(2-Aminoanilino)-2,5-Dihydrothiophene-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.