Description

(S)-1-Phenyl-2-Propyn-1-Ol is a chiral secondary alcohol featuring a phenyl and a propargyl group, making it a versatile chiral building block in organic synthesis. Its enantiopure form is critical for achieving high stereoselectivity in the production of advanced pharmaceutical intermediates and fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity chiral synthons for asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) for central nervous system (CNS) drugs, antivirals, and other therapeutic agents.
• Asymmetric Catalyst Ligand: Used in the development and preparation of chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials where optical purity is paramount.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	(S)-1-Phenyl-2-Propyn-1-Ol
CAS No.	61317-73-5
Molecular Formula	C9H8O
Molecular Weight	132.16 g/mol
Synonyms	(S)-1-Phenylprop-2-yn-1-ol; (S)-α-Propargylbenzyl Alcohol; (S)-Phenylpropargyl Alcohol; (S)-1-Phenyl-2-propynol; (S)-1-Phenylpropynol; (S)-Phenyl Propargyl Carbinol; (S)-PPC; (S)-1-Phenyl-2-propynyl Alcohol
EINECS	Contact for details

Quality Control

Our (S)-1-Phenyl-2-Propyn-1-Ol is produced under strict quality management systems. Each batch is characterized and tested to ensure high chemical and enantiomeric purity, typically meeting standards suitable for pharmaceutical R&D and GMP starting material applications. Comprehensive analytical data, including chiral HPLC for enantiomeric excess (ee) determination, is provided. Certificates of Analysis (COA) are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.