Description

(1S,2R,4R)-Bicyclo[2.2.1]Heptan-2-Ol CAS NO 61277-90-5 is a high-purity, chiral bicyclic alcohol derivative of norbornane, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its defined stereochemistry and rigid molecular framework make it invaluable for constructing complex molecules with precise three-dimensional architecture. This compound is essential for research and development in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients, ligands, and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides, where its stereochemistry can influence biological activity and environmental persistence.
• Catalyst & Ligand Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Flavor & Fragrance Chemistry: Employed in the synthesis of complex, naturally-derived odorants and flavoring agents with specific sensory profiles.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of novel polymers with unique thermal or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including new reaction development and stereochemical studies.

Basic Information

Product Name	(1S,2R,4R)-Bicyclo[2.2.1]Heptan-2-Ol
CAS No.	61277-90-5
Molecular Formula	C7H12O
Molecular Weight	112.17 g/mol
Synonyms	(1S,2R,4R)-2-Norborneol; (1S,2R,4R)-2-Hydroxybicyclo[2.2.1]heptane; endo-(1S,2R,4R)-Bicyclo[2.2.1]heptan-2-ol; (-)-endo-Norborneol; (1S,2R,4R)-Norbornan-2-ol; L-(-)-endo-Borneol (stereoisomer); Bicyclo[2.2.1]heptan-2-ol, (1S,2R,4R)-
EINECS	Contact for details

Quality Control

Our (1S,2R,4R)-Bicyclo[2.2.1]Heptan-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request. We support custom purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. This material is easily oxidized; ensure containers are properly sealed after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	152 - 156 °C
Specific Rotation [α]	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.