Description

α-Amino-2-Thiopheneacetonitrile is a versatile heterocyclic building block featuring both amino and nitrile functional groups on a thiophene scaffold. This compound is valued for its role as a key synthetic intermediate in the development of complex organic molecules, particularly in pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides, leveraging the bioactivity of the thiophene moiety.
• Material Science Research: Serves as a building block for creating advanced organic materials, such as conductive polymers, organic semiconductors, and ligands for catalysis.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and other tools for biochemical research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.

Basic Information

Product Name	α-Amino-2-Thiopheneacetonitrile
CAS No.	61261-50-5
Molecular Formula	C7H6N2S
Molecular Weight	150.20 g/mol
Synonyms	2-(Aminomethyl)thiophene-3-carbonitrile; 3-Cyano-2-thiophenemethylamine; (3-Cyano-2-thienyl)methanamine; 2-Thiopheneacetonitrile, α-amino-; α-Amino-2-thiopheneacetonitrile; 2-(Aminomethyl)-3-thiophenecarbonitrile; 3-Thiophenecarbonitrile, 2-(aminomethyl)-
EINECS	Contact for details

Quality Control

Our α-Amino-2-Thiopheneacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to quality supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.