Description

Bicyclo[1.1.0]Butane-1-Carboxylic Acid, 3-(Aminocarbonyl)- (9Ci) is a specialized bicyclic organic compound featuring a strained [1.1.0]butane core functionalized with both carboxylic acid and carboxamide groups. This unique molecular architecture makes it a valuable and versatile building block in advanced synthetic chemistry, particularly for constructing complex, three-dimensional frameworks. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, ligand synthesis, and materials science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring rigid, three-dimensional scaffolds to modulate biological activity and selectivity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its unique structure can contribute to novel modes of action.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis and organometallic chemistry due to its steric and electronic properties.
• Materials Science Precursor: Acts as a building block for advanced polymers and functional materials with tailored thermal or mechanical properties.
• Academic and R&D: Utilized in fundamental research to study strain-release chemistry, cycloaddition reactions, and the properties of small, strained ring systems.
• Chemical Biology Probe Synthesis: Incorporated into molecular probes to study enzyme function or protein-protein interactions, leveraging its compact, functionalized structure.

Basic Information

Product Name	Bicyclo[1.1.0]Butane-1-Carboxylic Acid, 3-(Aminocarbonyl)- (9Ci)
CAS No.	61168-43-2
Molecular Formula	C6H7NO3
Molecular Weight	141.13 g/mol
Synonyms	3-Carbamoylbicyclo[1.1.0]butane-1-carboxylic acid; 1-Carboxy-3-carbamoylbicyclo[1.1.0]butane; Bicyclo[1.1.0]butane-1-carboxylic acid, 3-carbamoyl-; 3-Aminocarbonylbicyclo[1.1.0]butane-1-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[1.1.0]Butane-1-Carboxylic Acid, 3-(Aminocarbonyl)- is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, maintaining the material at 2-8°C under an inert atmosphere is recommended to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.