Description

2-[(2-Phenyl-1H-Indol-3-Yl)Thio]Ethanamine is a specialized organic compound featuring a unique indole-thioether-amine scaffold, making it a valuable intermediate for advanced chemical synthesis. This compound is critical for research and development in pharmaceutical chemistry, where its structure serves as a key building block for novel active molecules. It is primarily sought after by fine chemical manufacturers, pharmaceutical R&D laboratories, and academic institutions engaged in medicinal chemistry and heterocyclic compound research.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new pharmacophores with enhanced biological activity.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic systems due to its reactive amine and thioether functional groups.
• Biochemical Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme inhibition and receptor binding.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents and pesticides.
• Material Science: Explored for the synthesis of organic semiconductors and advanced polymeric materials with specific electronic properties.

Basic Information

Product Name	2-[(2-Phenyl-1H-Indol-3-Yl)Thio]Ethanamine
CAS No.	61021-64-5
Molecular Formula	C₁₆H₁₆N₂S
Molecular Weight	268.38 g/mol
Synonyms	2-[(2-Phenyl-1H-indol-3-yl)sulfanyl]ethanamine; 2-(2-Phenyl-1H-indol-3-ylthio)ethanamine; Ethanamine, 2-[(2-phenyl-1H-indol-3-yl)thio]-; 2-(2-Phenylindol-3-ylthio)ethylamine; N-(2-Thio(2-phenyl-1H-indol-3-yl))ethylamine; 3-[(2-Aminoethyl)thio]-2-phenyl-1H-indole; 2-Phenyl-3-(2-aminoethylthio)indole
EINECS	Contact for details

Quality Control

Our production of 2-[(2-Phenyl-1H-Indol-3-Yl)Thio]Ethanamine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques, including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.