Description

L-5-Hydroxytryptophan Methyl Ester Hydrochloride is a chemically modified derivative of the essential amino acid precursor 5-HTP. This compound is valued for its enhanced stability and bioavailability compared to its parent molecule, making it a crucial intermediate in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and pharmaceutical manufacturers developing neurochemical agents, serotonin-related therapeutics, and high-purity reference standards.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel serotonergic compounds and central nervous system (CNS) active pharmaceuticals.
• Biochemical Research: Used as a standard or reagent in neuroscience and metabolic pathway studies related to serotonin synthesis and function.
• Reference Standard: Serves as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quality control in API (Active Pharmaceutical Ingredient) manufacturing.
• Preclinical Development: Employed in the development and testing of prodrug formulations aimed at improving blood-brain barrier penetration.
• Chemical Synthesis: An important precursor for further chemical modifications to create libraries of compounds for pharmacological screening.

Basic Information

Product Name	L-5-Hydroxytryptophan Methyl Ester Hydrochloride
CAS No.	60971-91-7
Molecular Formula	C12H15ClN2O3
Molecular Weight	270.71 g/mol
Synonyms	5-HTP Methyl Ester HCl; L-5-HTP Methyl Ester Hydrochloride; Methyl (S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoate hydrochloride; 5-Hydroxy-L-tryptophan methyl ester hydrochloride; (S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propionic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our L-5-Hydroxytryptophan Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets stringent specifications for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.