Description

(S)-(-)-n-(1-Phenylethyl)Maleimide is a high-purity chiral maleimide derivative, a crucial building block in asymmetric synthesis and advanced material science. Its value lies in its role as a versatile Michael acceptor and dienophile, enabling the stereoselective construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, where precise chirality control is paramount for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research.
• Asymmetric Synthesis: Used in Diels-Alder reactions and Michael additions to introduce the maleimide moiety with high stereoselectivity.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored thermal and mechanical properties.
• Bioconjugation: Useful for the selective modification of proteins, peptides, and antibodies via thiol-maleimide chemistry, leveraging its chiral center for targeted labeling.
• Agrochemical Research: Serves as a precursor in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for liquid crystals, organic semiconductors, and other advanced organic electronic materials.

Basic Information

Product Name	(S)-(-)-n-(1-Phenylethyl)Maleimide
CAS No.	60925-76-0
Molecular Formula	C12H11NO2
Molecular Weight	201.22 g/mol
Synonyms	(S)-(-)-1-Phenylethylmaleimide; (S)-N-(1-Phenylethyl)maleimide; (S)-N-(α-Methylbenzyl)maleimide; (S)-(-)-N-(α-Methylbenzyl)maleimide; (S)-N-(1-Phenylethyl)-2,5-dihydro-2,5-dioxo-1H-pyrrole; (S)-(-)-N-(1-Phenylethyl)-2,5-pyrroledione; (S)-N-(1-Phenylethyl)-1H-pyrrole-2,5-dione
EINECS	Contact for details

Quality Control

Our (S)-(-)-n-(1-Phenylethyl)Maleimide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting R&D and production standards. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (typically >98%), enantiomeric excess (ee), and related substances is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.