Description

(S)-3-n-Cbz-Amino-Succinimide CAS NO 60846-91-5 is a high-purity, chiral succinimide derivative protected with a carboxybenzyl (Cbz) group, serving as a critical chiral building block in advanced organic synthesis. Its primary value lies in enabling the stereoselective construction of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and other bioactive compounds. This intermediate is essential for research and production teams in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality chiral synthons for peptide mimetics and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of peptide-based drugs and protease inhibitors.
• Asymmetric Synthesis: Used as a chiral auxiliary or building block for constructing stereocenters in complex organic molecules.
• Peptidomimetic Research: Integral for developing peptide mimics where the succinimide scaffold is used to modulate biological activity and stability.
• API Development: Employed in the research and scale-up phases of new active pharmaceutical ingredient (API) manufacturing.
• Bioconjugation Chemistry: Can be utilized in the preparation of labeled compounds or antibody-drug conjugates (ADCs) due to its reactive imide and protected amine functionalities.
• Academic & Industrial R&D: Serves as a valuable reagent for method development and exploring new synthetic pathways in medicinal chemistry.

Basic Information

Product Name	(S)-3-n-Cbz-Amino-Succinimide
CAS No.	60846-91-5
Molecular Formula	C12H12N2O4
Molecular Weight	248.23 g/mol
Synonyms	(S)-3-(Benzyloxycarbonylamino)succinimide; (S)-3-(Cbz-Amino)succinimide; (S)-1-[(Benzyloxy)carbonyl]-2,5-pyrrolidinedione; (S)-N-Cbz-Asparagine Anhydride; (3S)-3-[[(Benzyloxy)carbonyl]amino]-2,5-dihydro-1H-pyrrole-2,5-dione; (S)-3-(N-Carbobenzyloxyamino)succinimide; Z-D-Asu-OH; Z-D-Asparagine anhydride
EINECS	Contact for details

Quality Control

Our (S)-3-n-Cbz-Amino-Succinimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards suitable for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.