Description

(S)-(+)-3-Chloro-1,2-Propanediol is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry is critical for producing enantiomerically pure pharmaceuticals and fine chemicals, ensuring precise biological activity and regulatory compliance. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where optical purity directly impacts product efficacy and safety.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-blockers, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a versatile precursor for chiral ligands, catalysts, and complex organic molecules in research and development.
• Biochemical Research: Employed in studies of enzyme mechanisms and as a standard for analytical method development in chiral separations.

Basic Information

Product Name	(S)-(+)-3-Chloro-1,2-Propanediol
CAS No.	60827-45-4
Molecular Formula	C3H7ClO2
Molecular Weight	110.54 g/mol
Synonyms	(S)-(+)-3-Chloropropane-1,2-diol; (S)-3-Chloro-1,2-propanediol; (S)-3-Chloropropylene Glycol; (S)-α-Chlorohydrin; (S)-3-MCPD; (S)-3-Chloro-1,2-dihydroxypropane; (S)-Glycidyl Chloride Hydrolysis Product (S-enantiomer)
EINECS	Contact for details

Quality Control

Our (S)-(+)-3-Chloro-1,2-Propanediol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing specific results for chiral purity, chemical purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.