Description

3-Chloro-4-Fluorothiophenol is a versatile organosulfur building block characterized by its thiol (-SH) group and halogenated aromatic ring. This compound matters for its role as a key intermediate in the synthesis of more complex molecules, particularly in advanced material science and pharmaceutical development. Industries that require it include agrochemical research, pharmaceutical manufacturing, and specialty polymer production, where it is used to introduce specific functional groups and modify material properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated thiophenol motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the chloro-fluoro-thiophenol structure imparts specific biological activity.
• Liquid Crystal & OLED Material Precursor: Acts as a key intermediate in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification Agent: Employed to introduce thiol functional groups into polymer chains, altering properties like adhesion, cross-linking density, and chemical resistance.
• Ligand Synthesis for Catalysis: Utilized in the preparation of specialized ligands for metal-catalyzed coupling reactions in fine chemical synthesis.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new synthetic pathways and novel compound libraries.

Basic Information

Product Name	3-Chloro-4-Fluorothiophenol
CAS No.	60811-23-6
Molecular Formula	C6H4ClFS
Molecular Weight	162.61 g/mol
Synonyms	3-Chloro-4-fluorobenzenethiol; 4-Fluoro-3-chlorothiophenol; 3-Chloro-4-fluorophenyl mercaptan; (3-Chloro-4-fluorophenyl)thiol; Benzenethiol, 3-chloro-4-fluoro-; 60811-23-6; 3-Cl-4-F-C6H3SH
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluorothiophenol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and assay. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.