Description

8-Iodo-1-Octyne is a versatile alkyne building block featuring a terminal iodo substituent, enabling diverse cross-coupling and functionalization reactions. Its value lies in providing a unique bifunctional handle for constructing complex molecular architectures in organic synthesis and materials science. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality raw materials for their R&D and production processes.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring alkyne or iodinated motifs.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where its reactive groups allow for the introduction of specific functional properties.
• Material Science Research: Acts as a monomer or precursor in the creation of specialized polymers, liquid crystals, and other functional materials.
• Cross-Coupling Reactions: A valuable substrate in Sonogashira, Heck, and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Chemical Biology Probes: Utilized in click chemistry (e.g., copper-catalyzed azide-alkyne cycloaddition) for labeling biomolecules and developing diagnostic tools.
• Organic Synthesis Building Block: Enables the straightforward introduction of an eight-carbon chain with terminal alkyne and iodo functionalities for further derivatization.

Basic Information

Item	Detail
Product Name	8-Iodo-1-Octyne
CAS No.	60754-50-9
Molecular Formula	C8H13I
Molecular Weight	236.09 g/mol
Synonyms	1-Octyne, 8-iodo-; 8-Iodo-1-octyne; 8-Iodooct-1-yne; 1-Iodo-7-heptyne; Oct-1-yn-8-yl iodide; 7-Heptyn-1-yl iodide; Terminal iodo alkyne C8
EINECS	Contact for details

Quality Control

Our 8-Iodo-1-Octyne is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to verify identity, potency, and impurity profiles. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with your specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.