Description

Nisbuterol is a selective β-2 adrenergic receptor agonist with significant pharmacological activity. This compound is valued for its potent bronchodilatory effects, making it a critical intermediate in the development of advanced respiratory therapeutics. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of next-generation asthma and chronic obstructive pulmonary disease (COPD) treatments. Our supply of Nisbuterol CAS NO 60734-87-4 ensures high purity and batch-to-batch consistency for reliable research and production outcomes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potent bronchodilator medications for respiratory conditions.
• Research & Development: Used in preclinical and clinical studies to investigate β-2 adrenergic receptor mechanisms and therapeutic efficacy.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create novel analogs with optimized pharmacological profiles.
• Veterinary Medicine: Potential application in developing treatments for respiratory distress in animals.

Basic Information

Product Name	Nisbuterol
CAS No.	60734-87-4
Molecular Formula	C13H20N2O3
Molecular Weight	252.31 g/mol
Synonyms	Nisbuterol; 4-Amino-3,5-dichloro-α-[[(1,1-dimethylethyl)amino]methyl]benzenemethanol; (R*,S*)-(±)-4-Amino-3,5-dichloro-α-[[(1,1-dimethylethyl)amino]methyl]benzenemethanol; (±)-Nisbuterol; rac-Nisbuterol; DL-Nisbuterol; 60734-87-4; Benzenemethanol, 4-amino-3,5-dichloro-α-[[(1,1-dimethylethyl)amino]methyl]-
EINECS	Contact for details

Quality Control

Our Nisbuterol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, NMR) to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) documenting all test results are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.