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2-Bromo-5-Chlorobenzyl Alcohol CAS NO 60666-70-8


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CAS No.:60666-70-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Bromo-5-Chlorobenzyl Alcohol is a versatile halogenated benzyl alcohol derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive benzylic alcohol and halogen handles for selective functionalization, enabling the construction of complex molecular architectures. This compound is primarily needed by pharmaceutical, agrochemical, and specialty chemical R&D sectors for the development of active ingredients and novel materials.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the halogenated aromatic core contributes to biological activity.
  • Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing halogenated aromatic compounds used in electronic display technologies and organic light-emitting diodes.
  • Polymer & Resin Modifier: Acts as a monomer or cross-linking agent to introduce halogen and hydroxyl functionality into polymer chains, altering thermal and physical properties.
  • Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions due to its reactive bromo and chloro substituents.
  • Dye & Pigment Intermediate: Utilized in the manufacture of specialized halogenated dyes and colorants for high-performance applications.

Basic Information

Product Name 2-Bromo-5-Chlorobenzyl Alcohol
CAS No. 60666-70-8
Molecular Formula C7H6BrClO
Molecular Weight 221.48 g/mol
Synonyms (2-Bromo-5-chlorophenyl)methanol; 2-Bromo-5-chlorobenzenemethanol; 1-Bromo-4-chloro-2-(hydroxymethyl)benzene; 5-Chloro-2-bromobenzyl alcohol; α-Hydroxy-2-bromo-5-chlorotoluene; Benzenemethanol, 2-bromo-5-chloro-; 2-Bromo-5-chloro-α-hydroxytoluene
EINECS Contact for details

Quality Control

Our 2-Bromo-5-Chlorobenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Assay (HPLC) ≥98.0%
Melting Point Contact for details
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm
Related Substances (HPLC) Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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