Description

Methylamine-13C Hydrochloride is a stable, isotopically labeled salt of methylamine, where the central carbon atom is the carbon-13 isotope. This product is essential for advanced analytical and research applications requiring precise molecular tracking and quantification. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard, a metabolic tracer, and in the synthesis of labeled compounds.

Application

• Internal standard for the accurate quantification of methylamine and related compounds in complex matrices via LC-MS (Liquid Chromatography-Mass Spectrometry) and GC-MS (Gas Chromatography-Mass Spectrometry).
• Critical reagent in the synthesis of carbon-13 labeled active pharmaceutical ingredients (APIs) and intermediates for drug metabolism and pharmacokinetic (DMPK) studies.
• Tracer compound in metabolic pathway research and environmental fate studies to track the transformation of methylamine.
• Use in nuclear magnetic resonance (NMR) spectroscopy as a standard for chemical shift referencing and structural elucidation.
• Preparation of isotopically labeled standards for clinical diagnostics and forensic analysis.
• Research applications in biochemistry and molecular biology investigating methylation processes and one-carbon metabolism.

Basic Information

Product Name	Methylamine-13C Hydrochloride
CAS No.	60656-93-1
Molecular Formula	13CH3NH2·HCl
Molecular Weight	68.52 g/mol
Synonyms	Methylamine-13C HCl; (13C)Methylamine hydrochloride; Monomethylamine-13C hydrochloride; Aminomethane-13C hydrochloride; Methanamine-13C hydrochloride; 13C-Labeled methylamine HCl; Methylamine (13C) hydrochloride; [13C]Methylamine hydrochloride
EINECS	Contact for details

Quality Control

Our Methylamine-13C Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and isotopic enrichment, with specifications typically meeting or exceeding 99% chemical purity and 99 atom % 13C. Certificates of Analysis (COA) detailing batch-specific results for identity, purity, isotopic enrichment, and residual solvents are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0 %
Isotopic Purity (13C)	≥ 99 atom %
Chemical Purity (HPLC)	≥ 99.0 %
Water Content (KF)	≤ 0.5 %
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.