Description

tert-Butyl (1H-Indol-3-Yl)Methylcarbamate is a protected indole derivative, a crucial building block in advanced organic synthesis. Its primary value lies in serving as a versatile synthetic intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), especially those targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing the indole scaffold.
• Medicinal Chemistry Research: Used in the discovery and optimization phase for building compound libraries and exploring structure-activity relationships (SAR).
• Peptidomimetic Synthesis: Serves as a protected amino acid analog for constructing peptide-like molecules with enhanced stability or bioavailability.
• Agrochemical Development: Intermediate in the research and production of advanced crop protection agents and plant growth regulators.
• Academic & Contract Research: Fundamental reagent for university laboratories and CROs (Contract Research Organizations) conducting studies in heterocyclic chemistry.
• Process Chemistry: Used in scale-up and route development for the commercial manufacturing of complex organic molecules.

Basic Information

Product Name	tert-Butyl (1H-Indol-3-Yl)Methylcarbamate
CAS No.	60524-00-7
Molecular Formula	C₁₄H₁₈N₂O₂
Molecular Weight	246.31 g/mol
Synonyms	tert-Butyl N-[(1H-indol-3-yl)methyl]carbamate; 1,1-Dimethylethyl N-[(1H-indol-3-yl)methyl]carbamate; Boc-3-indolylmethylamine; (1H-Indol-3-ylmethyl)-carbamic acid tert-butyl ester; N-Boc-3-(aminomethyl)indole; N-(tert-Butoxycarbonyl)-1H-indol-3-ylmethanamine; 3-[(tert-Butoxycarbonylamino)methyl]indole; N-Boc-indole-3-methylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl (1H-Indol-3-Yl)Methylcarbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.