Description

7-Chloro-3,4-Dihydroisoquinoline is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core structure serves as a privileged scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This intermediate is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), fine chemicals, and novel compounds for material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various therapeutic agents, including potential central nervous system (CNS) drugs and cardiovascular medications.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display technologies.
• Ligand and Catalyst Development: Utilized to create novel nitrogen-containing ligands for transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers, dyes, and photoactive materials.
• Academic and R&D Laboratories: A valuable compound for methodological studies and exploring new chemical reactions in heterocyclic chemistry.

Basic Information

Product Name	7-Chloro-3,4-Dihydroisoquinoline
CAS No.	60518-41-4
Molecular Formula	C9H8ClN
Molecular Weight	165.62 g/mol
Synonyms	7-Chloro-1,2,3,4-tetrahydroisoquinoline; 7-Chloro-3,4-dihydro-2H-isoquinoline; 7-Chloro-1,2,3,4-tetrahydro-isoquinoline; 7-Chloro-THIQ; 7-Cl-DHIQ; 7-Chloro-3,4-dihydroisoquinoline base; 7-Chloro-2,3-dihydro-1H-isoquinoline (tautomer)
EINECS	Contact for details

Quality Control

Our 7-Chloro-3,4-Dihydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.