Description

Methadone α-Naphtalenesulfonate is a pharmaceutical salt form of the synthetic opioid analgesic, methadone. This specific salt form is utilized to enhance the stability, solubility, or crystallinity of the active pharmaceutical ingredient (API) for formulation purposes. It is a critical intermediate or reference standard in the research, development, and quality control of controlled substance pharmaceuticals. This product is essential for analytical laboratories, pharmaceutical R&D departments, and manufacturers requiring high-purity chemical standards.

Application

• Pharmaceutical Reference Standard: Used as a certified standard in HPLC, GC, and other analytical methods for the quantification and identification of methadone in drug formulations and biological samples.
• Analytical Research & Method Development: Serves as a key material for developing and validating new analytical protocols in forensic, clinical, and regulatory testing laboratories.
• Controlled Substance Research: Employed in pharmacological and biochemical research studies investigating opioid receptor interactions, metabolism, and related therapeutic pathways.
• Pharmaceutical Intermediate: Acts as a precursor or an intermediate in the synthesis and manufacturing process of specific methadone-based pharmaceutical products.
• Quality Control & Assurance: Critical for in-process testing and final release testing to ensure the identity, potency, and purity of methadone-containing drug products against a known benchmark.

Basic Information

Product Name	Methadone α-Naphtalenesulfonate
CAS No.	60463-94-7
Molecular Formula	C21H27NO · C10H8O3S
Molecular Weight	Contact for details
Synonyms	Methadone 1-Naphthalenesulfonate; Methadone Naphthalene-1-sulfonate; Methadone α-Naphthalenesulfonic Acid Salt; (±)-6-Dimethylamino-4,4-diphenyl-3-heptanone 1-Naphthalenesulfonate; DL-Methadone 1-Naphthalenesulfonate; Heptanal, 6-(dimethylamino)-4,4-diphenyl-5-methyl-, α-naphthalenesulfonate
EINECS	Contact for details

Quality Control

Our Methadone α-Naphtalenesulfonate is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and composition. Certificates of Analysis (COA) detailing results from tests such as HPLC assay, related substances, residual solvents, and identification are provided and traceable to high-purity reference materials. We support compliance needs for research and development under current Good Manufacturing Practice (cGMP) principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store in accordance with all local, national, and international regulations for controlled substances or pharmaceutical materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.