Description

Ethyl 2-[(2-Chloroacetyl)Amino]-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate is a high-purity synthetic intermediate characterized by its fused tetrahydrobenzothiophene core and reactive chloroacetyl amide moiety. This compound is of significant value in pharmaceutical research and development, serving as a critical building block for the synthesis of novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used as a building block for developing new active ingredients in herbicides, fungicides, or insecticides, leveraging its heterocyclic structure.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study biological pathways and protein function in academic and industrial research settings.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the efficient, large-scale production of target molecules.
• Custom Synthesis & Contract Manufacturing: A vital starting material for specialty chemical manufacturers offering bespoke synthesis services to clients.

Basic Information

Product Name	Ethyl 2-[(2-Chloroacetyl)Amino]-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate
CAS No.	60442-41-3
Molecular Formula	C₁₅H₁₈ClNO₃S
Molecular Weight	327.82 g/mol
Synonyms	Ethyl 2-(2-chloroacetamido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-[(2-Chloroacetyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl ester; 3-Carbethoxy-2-(2-chloroacetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene; 60442-41-3; Tetrahydrobenzothiophene-3-carboxylate derivative
EINECS	Contact for details

Quality Control

Our Ethyl 2-[(2-Chloroacetyl)Amino]-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.