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2-n-Hexadecanoylamino-4-Nitrophenylphosphorylcholine CAS NO 60438-73-5


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CAS No.:60438-73-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-n-Hexadecanoylamino-4-Nitrophenylphosphorylcholine is a specialized synthetic phospholipid derivative with a chromogenic nitrophenyl group. This compound is valued for its role as a key biochemical tool in membrane biophysics and enzymatic research. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying phospholipase activity, membrane interactions, and developing diagnostic assays.

Application

  • Phospholipase Substrate: Acts as a chromogenic substrate for the detection and kinetic study of phospholipase A2 (PLA2) and other phospholipase enzymes.
  • Biochemical Research: Used in fundamental research on lipid metabolism, membrane dynamics, and cell signaling pathways.
  • Diagnostic Assay Development: Employed in the development of in vitro diagnostic kits for measuring enzymatic activity in clinical and research samples.
  • Membrane Model Systems: Incorporated into liposomes and other artificial membrane systems to study lipid-protein interactions.
  • Pharmaceutical Screening: Serves as a tool compound in high-throughput screening for identifying potential inhibitors of phospholipase enzymes.

Basic Information

Product Name 2-n-Hexadecanoylamino-4-Nitrophenylphosphorylcholine
CAS No. 60438-73-5
Molecular Formula C₂₉H₅₂N₃O₇P
Molecular Weight 585.71 g/mol
Synonyms Hexadecanoylamino Nitrophenylphosphorylcholine; 2-Hexadecanoylamino-4-nitrophenyl Phosphorylcholine; C16-NPPC; Nitrophenylphosphorylcholine Palmitamide; 1-Hexadecanoyl-2-(4-nitrophenylphosphoryl)-sn-glycero-3-phosphocholine analog; PLA2 Substrate; Chromogenic Phospholipid Substrate; 4-Nitrophenyl Phosphorylcholine derivative
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Quality Control

Our 2-n-Hexadecanoylamino-4-Nitrophenylphosphorylcholine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95%
Assay ≥ 98% (by titration)
Water Content (KF) ≤ 2.0%
Solubility Soluble in chloroform, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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