Description

Methyl 1-(Phenylsulfonyl)-1H-Indole-2-Carboxylate is a high-purity, synthetically valuable sulfonated indole derivative. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of biologically active indole-based compounds, including potential kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Organic Synthesis Building Block: The phenylsulfonyl group acts as a versatile protecting group and directing agent for further functionalization of the indole core in complex molecule assembly.
• Material Science Precursor: Employed in the research of organic electronic materials, such as novel semiconductors or light-emitting compounds.
• Academic & Contract Research: Serves as a standard reagent in university and CRO laboratories for methodological studies and discovery chemistry.

Basic Information

Product Name	Methyl 1-(Phenylsulfonyl)-1H-Indole-2-Carboxylate
CAS No.	60376-48-9
Molecular Formula	C16H13NO4S
Molecular Weight	315.34 g/mol
Synonyms	Methyl 1-(benzenesulfonyl)-1H-indole-2-carboxylate; 1-(Phenylsulfonyl)indole-2-carboxylic Acid Methyl Ester; 1H-Indole-2-carboxylic acid, 1-(phenylsulfonyl)-, methyl ester; Methyl 1-(phenylsulfonyl)indole-2-carboxylate; 1-Benzenesulfonylindole-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 1-(Phenylsulfonyl)-1H-Indole-2-Carboxylate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Certificates of Analysis (COA) are provided with each shipment, detailing specifications such as assay, identity, and impurity profiles. We support cGMP-compliant manufacturing for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.