Description

2-Cyclobuten-1-One, 2-Chloro-4,4-Difluoro-3-Methoxy- is a highly functionalized cyclobutenone derivative, serving as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a reactive ketone and halogenated methoxy substituents, makes it a critical building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those requiring fluorinated or strained ring systems for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive scaffold to introduce specific functional groups.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of novel polymers with specialized thermal or optical properties.
• Organic Synthesis Building Block: Employed in [4+2] cycloaddition reactions and other ring-opening or functionalization strategies to access a wide array of carbocyclic and heterocyclic compounds.
• Fluorine Chemistry: Serves as a valuable substrate for studying the effects of difluoromethoxy groups on chemical reactivity and physical properties in molecular design.

Basic Information

Product Name	2-Cyclobuten-1-One, 2-Chloro-4,4-Difluoro-3-Methoxy-
CAS No.	60376-34-3
Molecular Formula	C5H3ClF2O2
Molecular Weight	168.53 g/mol
Synonyms	2-Chloro-4,4-difluoro-3-methoxy-2-cyclobuten-1-one; 3-Methoxy-2-chloro-4,4-difluorocyclobut-2-en-1-one; 2-Chloro-4,4-difluoro-3-methoxycyclobut-2-enone; 4,4-Difluoro-2-chloro-3-methoxy-2-cyclobuten-1-one; 60376-34-3; 2-Cyclobuten-1-one, 2-chloro-4,4-difluoro-3-methoxy-
EINECS	Contact for details

Quality Control

Every batch of 2-Cyclobuten-1-One, 2-Chloro-4,4-Difluoro-3-Methoxy- is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.