Description

7-(Trifluoromethyl)-1H-Indazol-3-Ylamine is a high-value, multi-functional heterocyclic building block featuring a reactive amine group on the indazole core. This compound matters for its critical role as a key intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the indazole scaffold.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a tag or linker in the design of chemical probes for studying enzyme function and protein interactions.
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry programs and novel heterocycle exploration.

Basic Information

Product Name	7-(Trifluoromethyl)-1H-Indazol-3-Ylamine
CAS No.	60330-35-0
Molecular Formula	C8H6F3N3
Molecular Weight	201.15 g/mol
Synonyms	3-Amino-7-(trifluoromethyl)-1H-indazole; 7-(Trifluoromethyl)-1H-indazol-3-amine; 1H-Indazol-3-amine, 7-(trifluoromethyl)-; 60330-35-0; 7-Trifluoromethyl-1H-indazol-3-ylamine; 3-Amino-7-trifluoromethylindazole; 7-Trifluoromethylindazol-3-amine
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)-1H-Indazol-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.