Description

2,4,6-Trichlorophenyl Phosphorodichloridate is a key organophosphorus intermediate with significant utility in advanced chemical synthesis. Its primary value lies in its role as a versatile phosphorylating and chlorinating agent, enabling the construction of complex molecular architectures. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and specialized polymers.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of nucleotide analogs, prodrugs, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of organophosphate insecticides, herbicides, and plant growth regulators.
• Polymer Chemistry: Serves as a monomer or modifier in the creation of flame-retardant polymers and specialty plastics.
• Ligand and Catalyst Preparation: Employed in the synthesis of phosphite and phosphoramidite ligands for asymmetric catalysis.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new phosphorylation methodologies.
• Peptide Synthesis: Can be utilized in the preparation of phosphate ester derivatives of amino acids and peptides.

Basic Information

Product Name	2,4,6-Trichlorophenyl Phosphorodichloridate
CAS No.	60223-35-0
Molecular Formula	C6H2Cl5O2P
Molecular Weight	312.31 g/mol
Synonyms	Phosphorodichloridic Acid, 2,4,6-Trichlorophenyl Ester; 2,4,6-Trichlorophenyl Phosphorodichloridite; Dichloro(2,4,6-Trichlorophenoxy)Phosphine Oxide; POCL2-O-C6H2Cl3; 2,4,6-Trichlorophenoxyphosphonic Dichloride
EINECS	Contact for details

Quality Control

Our 2,4,6-Trichlorophenyl Phosphorodichloridate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.