Description

(E)-1-(Trimethylsilyl)-3-Hepten-1-Yne CAS NO 60216-46-8 is a specialized organosilicon building block featuring both a silyl-protected alkyne and an alkene functionality. This unique structure makes it a valuable intermediate for advanced organic synthesis, particularly in the construction of complex molecules and materials. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise molecular assembly.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in cross-coupling and cycloaddition reactions.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactivity to create complex heterocyclic structures.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, dendrimers, and silicon-containing advanced materials.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing carbon-carbon bonds via Sonogashira, Heck, or other metal-catalyzed coupling reactions.
• Ligand and Catalyst Development: Useful precursor for creating novel ligands or organometallic complexes used in homogeneous catalysis.

Basic Information

Product Name	(E)-1-(Trimethylsilyl)-3-Hepten-1-Yne
CAS No.	60216-46-8
Molecular Formula	C₁₀H₁₈Si
Molecular Weight	166.34 g/mol
Synonyms	(E)-1-(Trimethylsilyl)-3-hepten-1-yne; 3-Hepten-1-yne, 1-(trimethylsilyl)-, (E)-; 1-Trimethylsilyl-(E)-3-hepten-1-yne; (E)-1-Trimethylsilyl-3-hepten-1-yne; TMS-protected enyne; (E)-3-Hepten-1-yn-1-yltrimethylsilane; 1-(Trimethylsilyl)-(3E)-3-hepten-1-yne
EINECS	Contact for details

Quality Control

Our production of (E)-1-(Trimethylsilyl)-3-Hepten-1-Yne adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for synthetic applications. Each lot undergoes comprehensive analysis, including purity assay and identity confirmation. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its highly volatile nature, keep the container tightly sealed when not in use and store at temperatures between 2°C and 8°C (refrigerated) for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Isomeric Purity ((E)-isomer, GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.