Description

(Z)-1-(Trimethylsilyl)-3-Hepten-1-Yne is a specialized organosilicon building block featuring both a terminal alkyne and an alkene group, protected by a trimethylsilyl moiety. This unique structure makes it a valuable reagent for advanced organic synthesis, particularly in cross-coupling reactions and the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel compounds and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for creating complex alkyne-containing scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactive functional groups for structural diversification.
• Material Science Research: Serves as a precursor in the development of advanced polymers, dendrimers, and organic electronic materials through controlled polymerization or functionalization.
• Cross-Coupling Reactions: An effective substrate in Sonogashira, Heck, and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for the stereoselective synthesis of natural products and complex organic molecules.
• Ligand and Catalyst Development: Used to synthesize novel ligands or organometallic complexes for catalytic applications.

Basic Information

Product Name	(Z)-1-(Trimethylsilyl)-3-Hepten-1-Yne
CAS No.	60216-45-7
Molecular Formula	C10H18Si
Molecular Weight	166.33 g/mol
Synonyms	(Z)-3-Hepten-1-yn-1-yltrimethylsilane; 1-Trimethylsilyl-(Z)-3-hepten-1-yne; (Z)-1-Trimethylsilyl-3-hepten-1-yne; 3-Hepten-1-yn-1-yltrimethylsilane, (Z)-; TMS-protected (Z)-3-hepten-1-yne; Trimethyl[(3Z)-3-hepten-1-yn-1-yl]silane
EINECS	Contact for details

Quality Control

Our (Z)-1-(Trimethylsilyl)-3-Hepten-1-Yne is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant regulatory frameworks for industrial and R&D use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place, ideally at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. This compound is moisture-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0% (Area %)
Isomeric Purity (Z-isomer, GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.