Description

3-Iodothiophene-2-Carboxylic Acid is a high-purity, functionalized heterocyclic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and catalyst design.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides with specific modes of action.
• Material Science: Serves as a monomer or functionalizing agent for creating conductive polymers and advanced organic electronic materials.
• Ligand & Catalyst Development: Employed to synthesize complex ligands for transition metal catalysis, enabling challenging cross-coupling reactions.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and diagnostic assay development.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and scale-up process optimization.

Basic Information

Product Name	3-Iodothiophene-2-Carboxylic Acid
CAS No.	60166-84-9
Molecular Formula	C5H3IO2S
Molecular Weight	253.04 g/mol
Synonyms	2-Thiophenecarboxylic acid, 3-iodo-; 3-Iodo-2-thiophenecarboxylic acid; 3-Iodothiophene-2-carboxylic acid; 3-Iodo-2-carboxythiophene; 3-Iodothiophene-2-carboxylate; 3-Iodo-2-thiophene carboxylic acid; 3-Iodo-2-thiophene acid; 3-Iodothiophene-2-carboxylic acid (CAS 60166-84-9)
EINECS	Contact for details

Quality Control

Our 3-Iodothiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and lot-to-lot consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.