Description

5-Methoxy-3-(Piperidin-4-Yl)-1H-Indole Hydrochloride is a high-purity, pharmaceutically relevant indole derivative supplied as a hydrochloride salt. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within the fields of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates targeting specific receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound: Employed in in-vitro assays to study biological pathways and enzyme interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP-scale production.
• Academic Research: Utilized in university and institutional labs for novel synthetic methodology development.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation.

Basic Information

Product Name	5-Methoxy-3-(Piperidin-4-Yl)-1H-Indole Hydrochloride
CAS No.	60155-65-9
Molecular Formula	C15H20N2O·HCl
Molecular Weight	280.80 g/mol
Synonyms	5-Methoxy-3-(4-piperidinyl)-1H-indole hydrochloride; 3-(Piperidin-4-yl)-5-methoxy-1H-indole HCl; 5-Methoxy-3-(4-piperidyl)indole hydrochloride; 1H-Indole, 5-methoxy-3-(4-piperidinyl)-, hydrochloride; 5-MeO-3-(4-piperidyl)indole HCl; 60155-65-9 (CAS); 5-Methoxy-3-(piperidin-4-yl)-1H-indole HCl salt
EINECS	Contact for details

Quality Control

Our 5-Methoxy-3-(Piperidin-4-Yl)-1H-Indole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with cGMP guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.