Description

2-[2,3-o-(1-Methylethylidene)-β-D-Ribofuranosyl]-4-Thiazolecarboxamide is a specialized nucleoside analogue with a modified ribose moiety and a thiazolecarboxamide functional group. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a synthetic intermediate or a building block for novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of antiviral, anticancer, or other biologically active nucleoside derivatives. The compound is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and research-grade purity.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic building block in the research and development of novel nucleoside-based drugs.
• Antiviral Agent Research: Investigated for its potential activity and as a precursor in the synthesis of compounds targeting viral polymerases.
• Anticancer Drug Development: Used in medicinal chemistry programs to create analogs that may interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related pathways.
• Chemical Biology Probes: Utilized in the design of molecular probes to study cellular processes involving nucleoside recognition.
• Process Chemistry: Acts as a starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2-[2,3-o-(1-Methylethylidene)-β-D-Ribofuranosyl]-4-Thiazolecarboxamide
CAS No.	60084-11-9
Molecular Formula	C12H16N2O5S
Molecular Weight	300.33 g/mol
Synonyms	4-Thiazolecarboxamide, 2-[2,3-O-(1-methylethylidene)-β-D-ribofuranosyl]-; 2-(2,3-O-Isopropylidene-β-D-ribofuranosyl)thiazole-4-carboxamide; Tiazofurin Isopropylidene Derivative; β-D-Ribofuranoside, 2,3-O-(1-methylethylidene)-, 4-thiazolecarboxylate; NSC 286193; 2,3-O-Isopropylidene-tiazofurin
EINECS	Contact for details

Quality Control

Our 2-[2,3-o-(1-Methylethylidene)-β-D-Ribofuranosyl]-4-Thiazolecarboxamide is manufactured under controlled conditions to ensure high purity and reliability for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all relevant specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.