Description

(+)-7-[[5-(3,6-Dihydroxy-2,2,6-Trimethylcyclohexyl)-3-Hydroxy-3-Methylpentyl]Oxy]-2H-1-Benzopyran-2-One is a high-purity, optically active coumarin derivative with a complex polyhydroxylated side chain, offering significant value as a key chiral intermediate or reference standard. This compound matters for its precise stereochemistry and functional groups, which are critical for research and development in advanced organic synthesis and pharmaceutical discovery. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel bioactive molecules or for analytical method development.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting specific enzymatic pathways.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, or NMR for method validation, quality control, and impurity profiling in related compound manufacturing.
• Biochemical Research: Employed in academic and industrial research to study structure-activity relationships (SAR) of coumarin-based compounds or as a probe in biological assays.
• Fine Chemical Synthesis: Acts as a starting material or advanced intermediate for the custom synthesis of complex natural product analogs or specialty chemicals.
• Agrochemical Development: Potential use as a precursor in the development of new, optically active crop protection agents with enhanced specificity.

Basic Information

Product Name	(+)-7-[[5-(3,6-Dihydroxy-2,2,6-Trimethylcyclohexyl)-3-Hydroxy-3-Methylpentyl]Oxy]-2H-1-Benzopyran-2-One
CAS No.	60077-54-5
Molecular Formula	C25H36O7
Molecular Weight	448.55 g/mol
Synonyms	(+)-7-[(5-(3,6-Dihydroxy-2,2,6-trimethylcyclohexyl)-3-hydroxy-3-methylpentyl)oxy]-2H-chromen-2-one; 7-[[5-(3,6-Dihydroxy-2,2,6-trimethylcyclohexyl)-3-hydroxy-3-methylpentyl]oxy]coumarin; (6R,7S)-7-[[5-[(1S,2R,5S)-3,6-Dihydroxy-2,2,6-trimethylcyclohexyl]-3-hydroxy-3-methylpentyl]oxy]-2H-1-benzopyran-2-one; Auraptene derivative; Decursinol derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (+)-7-[[5-(3,6-Dihydroxy-2,2,6-Trimethylcyclohexyl)-3-Hydroxy-3-Methylpentyl]Oxy]-2H-1-Benzopyran-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development use. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.