Description

(+)-7-[[5-(3-Acetyloxy-6-Hydroxy-2,2,6-Trimethylcyclohexyl)-3-Hydroxy-3-Methylpentyl]Oxy]-2H-1-Benzopyran-2-One is a high-purity, optically active coumarin derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and intermediate for developing novel therapeutic agents and bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for its unique structural framework.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly for cardiovascular and anti-inflammatory applications.
• Advanced Organic Synthesis: Serves as a versatile building block for constructing complex natural product analogs and heterocyclic compounds.
• Biochemical Research: Used in studies investigating enzyme inhibition, receptor binding, and other structure-activity relationships (SAR).
• Agrochemical Development: Intermediate for creating new generation plant growth regulators or protective agents with specific stereochemical requirements.
• Material Science Research: Potential monomer or additive for developing specialty polymers with specific optical or biological properties.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Item	Details
Product Name	(+)-7-[[5-(3-Acetyloxy-6-Hydroxy-2,2,6-Trimethylcyclohexyl)-3-Hydroxy-3-Methylpentyl]Oxy]-2H-1-Benzopyran-2-One
CAS No.	60077-53-4
Molecular Formula	C28H40O8
Molecular Weight	504.62 g/mol
Synonyms	(+)-7-Hydroxy-4-methylcoumarin 7-O-(5-(3-acetyloxy-6-hydroxy-2,2,6-trimethylcyclohexyl)-3-hydroxy-3-methylpentyl) ether; 7-[(5-(3-Acetyloxy-6-hydroxy-2,2,6-trimethylcyclohexyl)-3-hydroxy-3-methylpentyl)oxy]-4-methyl-2H-chromen-2-one; 7-[(5-(3-Acetyloxy-6-hydroxy-2,2,6-trimethylcyclohexyl)-3-hydroxy-3-methylpentyl)oxy]-4-methylcoumarin; A related derivative of Fraxetin; Optical isomer of a coumarin-terpene conjugate.
EINECS	Contact for details

Quality Control

Our (+)-7-[[5-(3-Acetyloxy-6-Hydroxy-2,2,6-Trimethylcyclohexyl)-3-Hydroxy-3-Methylpentyl]Oxy]-2H-1-Benzopyran-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.