Description

Avizafone is a synthetic benzodiazepine derivative, primarily recognized for its prodrug relationship to diazepam. This compound is of significant interest in pharmaceutical research and development due to its specific metabolic pathway and potential applications. It is a critical intermediate and reference standard for laboratories and manufacturers in the life sciences sector. Global industries engaged in neuropharmacology, analytical chemistry, and fine chemical synthesis require this high-purity material.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in drug testing and forensic analysis.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic precursor in the research and production of benzodiazepine-class therapeutics.
• Biochemical Research: Employed in preclinical studies to investigate the metabolism, pharmacokinetics, and structure-activity relationships of prodrug benzodiazepines.
• Analytical Chemistry: Utilized as an analytical standard in HPLC, GC-MS, and NMR for the identification and quantification of related substances.

Basic Information

Item	Details
Product Name	Avizafone
CAS No.	60067-15-4
Molecular Formula	C₂₂H₂₂ClN₃O₃
Molecular Weight	411.88 g/mol
Synonyms	Avizafone; N-Methyl-2-[(2-methyl-5-oxo-1H-1,4-benzodiazepin-3-yl)oxy]acetohydrazide; 3-(N'-Methylcarbamoylmethoxy)-1-methyl-5-phenyl-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Pro-Diazepam; NSC 332488; CM 7117; CB 8065
EINECS	Contact for details

Quality Control

Our Avizafone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support its use in research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.