Description

2H-Thiopyran-4-Carboxylicacid,4-Aminotetrahydro-2,5-Dimethyl-,(2Alpha,4Alpha,5Beta)- is a specialized heterocyclic building block featuring a thiopyran core with carboxylic acid and amine functionalities. This compound matters as a high-value intermediate for the synthesis of complex molecules, offering precise stereochemistry critical for pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique thiopyran structure for biological activity.
• Fine Chemical Synthesis: Serves as a precursor for complex ligands, catalysts, and specialty chemicals requiring specific stereochemical configurations.
• Academic & Industrial R&D: Employed in medicinal chemistry programs and material science research to explore new chemical spaces and structure-activity relationships.
• Peptidomimetic Development: Its structure makes it suitable for creating constrained peptide analogs and bioisosteres in drug design.

Basic Information

Product Name	2H-Thiopyran-4-Carboxylicacid,4-Aminotetrahydro-2,5-Dimethyl-,(2Alpha,4Alpha,5Beta)-
CAS No.	60046-38-0
Molecular Formula	C9H15NO2S
Molecular Weight	201.29 g/mol
Synonyms	4-Amino-2,5-dimethyltetrahydro-2H-thiopyran-4-carboxylic acid; (2α,4α,5β)-4-Amino-2,5-dimethyltetrahydro-2H-thiopyran-4-carboxylic acid; 4-Amino-2,5-dimethyltetrahydro-2H-thiopyran-4-carboxylic acid (stereoisomer); Tetrahydro-2,5-dimethyl-4-amino-2H-thiopyran-4-carboxylic acid; 60046-38-0; 2H-Thiopyran-4-carboxylic acid, 4-amino-2,5-dimethyltetrahydro-, (2α,4α,5β)-; 4-Amino-2,5-dimethylperhydro-2H-thiopyran-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2H-Thiopyran-4-Carboxylicacid,4-Aminotetrahydro-2,5-Dimethyl-,(2Alpha,4Alpha,5Beta)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and specific test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.