Description

2H-Thiopyran-4-Carboxylicacid,4-Aminotetrahydro-2,5-Dimethyl-,(2Alpha,4Beta,5Alpha)- is a specialized heterocyclic compound featuring a thiopyran core, an amino group, and a carboxylic acid functionality, making it a versatile chiral building block for advanced synthesis. This compound matters for its role as a key intermediate in the development of complex, high-value molecules, particularly in the pharmaceutical sector where its defined stereochemistry is critical. It is primarily needed by research and development chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used as a building block for developing new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Fine Chemical Synthesis: Employed in the production of complex, high-purity specialty chemicals for research and industrial applications.
• Ligand and Catalyst Development: The amino and carboxylic acid groups make it a candidate for developing chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or precursor for novel polymers and advanced materials with specific optical or electronic properties.
• Academic & Contract Research: A valuable compound for university laboratories and CROs (Contract Research Organizations) conducting fundamental research in organic and medicinal chemistry.

Basic Information

Product Name	2H-Thiopyran-4-Carboxylicacid,4-Aminotetrahydro-2,5-Dimethyl-,(2Alpha,4Beta,5Alpha)-
CAS No.	60046-37-9
Molecular Formula	C9H15NO2S
Molecular Weight	201.29 g/mol
Synonyms	4-Amino-2,5-dimethyltetrahydro-2H-thiopyran-4-carboxylic acid; (2α,4β,5α)-4-Amino-2,5-dimethyltetrahydro-2H-thiopyran-4-carboxylic acid; 4-Amino-2,5-dimethyltetrahydro-2H-thiopyran-4-carboxylic acid (2α,4β,5α)-; Tetrahydro-2,5-dimethyl-4-amino-2H-thiopyran-4-carboxylic acid; 60046-37-9; 2H-Thiopyran-4-carboxylic acid, 4-amino-2,5-dimethyltetrahydro-, (2α,4β,5α)-; 4-Amino-2,5-dimethyltetrahydro-2H-thiopyran-4-carboxylicacid
EINECS	Contact for details

Quality Control

Our 2H-Thiopyran-4-Carboxylicacid,4-Aminotetrahydro-2,5-Dimethyl-,(2Alpha,4Beta,5Alpha)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.