Description

1H-Pyrrolizin-1-One,5,6,7,7A-Tetrahydro-2-Methyl-3-(1-Methylethyl)-,(S)-(9Ci) is a high-purity chiral intermediate of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined pyrrolizine core, which serves as a critical building block for complex molecular architectures. This compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of new active pharmaceutical ingredients (APIs), especially in neurological and anti-inflammatory drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for stereoselective reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including novel ring-forming and functionalization reactions.
• Material Science Research: Investigated as a potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	1H-Pyrrolizin-1-One,5,6,7,7A-Tetrahydro-2-Methyl-3-(1-Methylethyl)-,(S)-(9Ci)
CAS No.	60026-52-0
Molecular Formula	C11H17NO
Molecular Weight	179.26 g/mol
Synonyms	(S)-5,6,7,7a-Tetrahydro-2-methyl-3-(propan-2-yl)-1H-pyrrolizin-1-one; (S)-5,6,7,7a-Tetrahydro-2-methyl-3-isopropyl-1H-pyrrolizin-1-one; (S)-2-Methyl-3-isopropyl-5,6,7,7a-tetrahydro-1H-pyrrolizin-1-one; (S)-Isopropylmethyltetrahydropyrrolizinone; (S)-Form of the pyrrolizinone derivative; 1H-Pyrrolizin-1-one, 5,6,7,7a-tetrahydro-2-methyl-3-(1-methylethyl)-, (7aS)-; (7aS)-5,6,7,7a-Tetrahydro-2-methyl-3-(propan-2-yl)-1H-pyrrolizin-1-one
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolizin-1-One derivative is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting R&D and production standards. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided to guarantee traceability and product integrity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.