Description

(-)-7-[(1,4,4A,5,6,7,8,8A-Octahydro-6-Hydroxy-2,5,5,8A-Tetramethylnaphthalen-1-Yl)Methoxy]-2H-1-Benzopyran-2-One CAS NO 60018-29-3 is a high-purity, optically active coumarin derivative with a complex, fused-ring structure. This compound is valued for its role as a key chiral intermediate in advanced organic synthesis, particularly for pharmaceuticals and bioactive molecules. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemistry in their synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel drug candidates, especially those targeting specific biological receptors.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.
• Agrochemical Research: Employed as a precursor in developing new active ingredients for crop protection with specific modes of action.
• Biochemical Research: Utilized in studies exploring enzyme inhibitors or modulators due to its coumarin core and specific stereochemistry.
• Material Science: Potential application as a monomer or functional additive in the development of advanced polymeric materials with specific optical properties.

Basic Information

Item	Details
Product Name	(-)-7-[(1,4,4A,5,6,7,8,8A-Octahydro-6-Hydroxy-2,5,5,8A-Tetramethylnaphthalen-1-Yl)Methoxy]-2H-1-Benzopyran-2-One
CAS No.	60018-29-3
Molecular Formula	C24H32O4
Molecular Weight	384.51 g/mol
Synonyms	(-)-7-[(1,4,4a,5,6,7,8,8a-Octahydro-6-hydroxy-2,5,5,8a-tetramethyl-1-naphthalenyl)methoxy]-2H-1-benzopyran-2-one; 7-[(1,4,4a,5,6,7,8,8a-Octahydro-6-hydroxy-2,5,5,8a-tetramethyl-1-naphthalenyl)methoxy]coumarin (enantiomer); 7-((1,4,4a,5,6,7,8,8a-Octahydro-6-hydroxy-2,5,5,8a-tetramethyl-1-naphthyl)methoxy)coumarin; CAS 60018-29-3; Light-sensitive coumarin derivative; Chiral coumarin intermediate.
EINECS	Contact for details

Quality Control

Our (-)-7-[(1,4,4A,5,6,7,8,8A-Octahydro-6-Hydroxy-2,5,5,8A-Tetramethylnaphthalen-1-Yl)Methoxy]-2H-1-Benzopyran-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC), to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.