Description

Benzenemethanol, A-Ethynyl-3,4-Dimethoxy- is a specialized aromatic alcohol building block featuring a terminal alkyne and dimethoxy substituents, making it a valuable intermediate for advanced organic synthesis. Its unique structure provides a versatile handle for click chemistry and cross-coupling reactions, enabling the construction of complex molecular architectures. This compound is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical development, and materials science for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its aromatic backbone for bioactive molecule design.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and resins with tailored properties.
• Click Chemistry Substrate: The terminal alkyne group makes it an ideal participant in Huisgen cycloaddition reactions for bioconjugation and polymer functionalization.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalytic systems.
• Fine Chemical Manufacturing: Intermediate in the multi-step synthesis of complex flavors, fragrances, and dyes.

Basic Information

Product Name	Benzenemethanol, A-Ethynyl-3,4-Dimethoxy-
CAS No.	6953-67-9
Molecular Formula	C11H12O3
Molecular Weight	192.21 g/mol
Synonyms	1-(3,4-Dimethoxyphenyl)-2-propyn-1-ol; 3,4-Dimethoxy-α-ethynylbenzyl Alcohol; α-Ethynyl-3,4-dimethoxybenzenemethanol; (3,4-Dimethoxyphenyl)(ethynyl)methanol; 3,4-Dimethoxy-α-ethynylbenzyl alcohol; 1-Ethynyl-3,4-dimethoxybenzyl alcohol
EINECS	Contact for details

Quality Control

Our production of Benzenemethanol, A-Ethynyl-3,4-Dimethoxy- (CAS 6953-67-9) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure consistency and meet the exacting standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.