Description

1-Chloro-3-Iodopropane is a versatile bifunctional alkylating agent and a key organic synthetic intermediate. This compound is valued for its reactivity, enabling the introduction of both chloro and iodo functional groups in a single molecule, which is critical for constructing complex molecular architectures. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in nucleophilic substitution reactions and cross-coupling chemistry.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and other bioactive molecules.
• Agrochemical Synthesis: Serves as a building block for herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the production of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Heck, Sonogashira) for carbon-carbon bond formation.
• Organic Synthesis: A key reagent for alkylation and chain-extension reactions in laboratory-scale and process chemistry.
• Ligand and Catalyst Preparation: Used to synthesize novel phosphine or nitrogen-based ligands for catalytic systems.

Basic Information

Product Name	1-Chloro-3-Iodopropane
CAS No.	6940-76-7
Molecular Formula	C3H6ClI
Molecular Weight	204.44 g/mol
Synonyms	3-Chloro-1-iodopropane; 3-Iodopropyl chloride; 1-Iodo-3-chloropropane; γ-Chloroiodopropane; 3-Chloropropyl iodide; NSC 9235; Propane, 1-chloro-3-iodo-; Iodochloropropane
EINECS	230-095-6

Quality Control

Our 1-Chloro-3-Iodopropane is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept tightly sealed and away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.85 - 1.90 g/mL
Refractive Index (n20D)	1.550 - 1.560

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.